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Mental Effects Of Anabolic Steroids. While the physical side effects of anabolic steroid use are visible and easy to notice, the mental side effects don't come to your attention immediately. What you should know, however, is that anabolic steroid use can and will negatively impact your brain and, consequently, your mood. The National Institute on Drug Abuse cautions about these effects: You may show signs of extreme and unreasonable paranoia You could become delusional Your judgment may become impaired You may become jealous of other people You may find yourself extremely irritable You may even have extreme mood swings You could experience hypomania, where you become hyperactive and elated You may also experience depression 10. The extent or intensity of your side effects will depend on the dose you take as well as the type of anabolic steroids you're using. 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